Last update 24 Mar 2026

CDH17-CD3-4-1BB tri-specific TCE(Excalipoint)

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms-
Target
4-1BB x CD3 x CDH17
Action
agonists, stimulants, antagonists
Mechanism
4-1BB agonists(Tumor necrosis factor receptor superfamily member 9 agonists), CD3 stimulants(T cell surface glycoprotein CD3 stimulants), CDH17 antagonists(Cadherin-17 antagonists)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Lepu Biopharma Co., Ltd.Lepu Biopharma Co., Ltd.Excalipoint Therapeutics Co., Ltd.
Active Organization-
Inactive Organization-
License Organization-
Drug Highest Phase-
First Approval Date-
Regulation-

Related

100 Clinical Results associated with CDH17-CD3-4-1BB tri-specific TCE(Excalipoint)
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100 Translational Medicine associated with CDH17-CD3-4-1BB tri-specific TCE(Excalipoint)
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100 Patents (Medical) associated with CDH17-CD3-4-1BB tri-specific TCE(Excalipoint)
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100 Deals associated with CDH17-CD3-4-1BB tri-specific TCE(Excalipoint)
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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