Last update 30 May 2025

Etoricoxib/tizanidine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MK-0663B
Target
COX-2 x α2A-AR
Action
inhibitors, agonists
Mechanism
COX-2 inhibitors(Cyclooxygenase-2 inhibitors), α2A-AR agonists(Alpha-2a adrenergic receptor agonists)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
Active Organization-
Inactive Organization-
License Organization-
Drug Highest Phase-
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC18H15ClN2O2S
InChIKeyMNJVRJDLRVPLFE-UHFFFAOYSA-N
CAS Registry202409-33-4
View All Structures (2)

Related

3
Clinical Trials associated with Etoricoxib/tizanidine
NCT06863662
/ RecruitingPhase 3
Efficacy and Safety of the Fixed-Dose Combination of Etoricoxib / Tizanidine Versus Etoricoxib in the Treatment of Patients With Acute Low Back Pain Associated to Muscle Spasm
NCT01979510
/ WithdrawnPhase 3
A Phase III Randomized Clinical Trial to Evaluate the Safety and Efficacy of an Etoricoxib and Tizanidine Fixed Dose Combination in Subjects With Moderate to Severe Acute Low Back Pain
ACTRN12612001152819
/ Not yet recruitingNot Applicable
An Open-Label, 2-Part, Single Dose, Randomized Study to Evaluate the Pharmacokinetics of a Probe Formulation of MK-0663B (etoricoxib/tizanidine MR) in Healthy Adult Subjects.
100 Clinical Results associated with Etoricoxib/tizanidine
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100 Translational Medicine associated with Etoricoxib/tizanidine
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100 Patents (Medical) associated with Etoricoxib/tizanidine
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100 Deals associated with Etoricoxib/tizanidine
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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