[Translation] A randomized, double-blind, placebo-controlled phase I clinical study of the safety, tolerability, pharmacokinetics and pharmacodynamics of HRS-9563 after a single subcutaneous injection in subjects with mild hypertension
主要目的:
1.评价HRS-9563在高血压受试者中单次皮下注射给药的安全性和耐受性
次要目的:
1.评价HRS-9563在高血压受试者中单次皮下注射给药的药代动力学(PK)特征
2.评价HRS-9563在高血压受试者中单次皮下注射给药的药效学(PD)特征
3.评价HRS-9563在高血压受试者中单次皮下注射给药的免疫原性特征
[Translation] Primary objectives:
1. To evaluate the safety and tolerability of a single subcutaneous injection of HRS-9563 in hypertensive subjects
Secondary objectives:
1. To evaluate the pharmacokinetic (PK) characteristics of a single subcutaneous injection of HRS-9563 in hypertensive subjects
2. To evaluate the pharmacodynamic (PD) characteristics of a single subcutaneous injection of HRS-9563 in hypertensive subjects
3. To evaluate the immunogenicity characteristics of a single subcutaneous injection of HRS-9563 in hypertensive subjects