Last update 24 Apr 2025

ALXN-2030

Overview

Basic Info

Drug Type
siRNA
Synonyms
ALXN 2030, ALXN2030
Target
C3
Action
inhibitors
Mechanism
C3 inhibitors(Complement C3 inhibitors)
Therapeutic Areas
Urogenital DiseasesImmune System Diseases
Active Indication
Kidney DiseasesRenal transplant rejection
Inactive Indication-
Originator Organization
Alexion Pharmaceuticals, Inc.Alexion Pharmaceuticals, Inc.
Active Organization
Alexion Pharmaceuticals, Inc.Alexion Pharmaceuticals, Inc.AstraZeneca PLCAstraZeneca PLC
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

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Related

2
Clinical Trials associated with ALXN-2030
NCT06744647
/ RecruitingPhase 2
A Phase 2, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate Efficacy and Safety of ALXN2030 in Adult Patients With Antibody-Mediated Rejection After Kidney Transplantation
NCT05501717
/ RecruitingPhase 1
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study of Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Subcutaneous ALXN2030 in Healthy Participants
100 Clinical Results associated with ALXN-2030
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100 Translational Medicine associated with ALXN-2030
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100 Patents (Medical) associated with ALXN-2030
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100 Deals associated with ALXN-2030
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Kidney DiseasesPhase 1
United Kingdom
AstraZeneca PLCAstraZeneca PLC
-
Renal transplant rejectionIND Approval
China
Alexion Pharmaceuticals, Inc.Alexion Pharmaceuticals, Inc.
24 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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