Last update 25 Nov 2024

VSA-003

Overview

Basic Info

Drug Type
siRNA
Synonyms
VSA 003, VSA-003, VSA003
Target
ANGPTL3
Mechanism
ANGPTL3 modulators(Angiopoietin like 3 modulators)
Therapeutic Areas
Endocrinology and Metabolic DiseaseOther DiseasesCongenital Disorders
Active Indication
Homozygous familial hypercholesterolemiaDyslipidemiasHyperlipoproteinemia Type II+ [3]
Inactive Indication-
Originator Organization
Visirna Biotechnology (Shanghai) Co., Ltd.
Active Organization
Visirna Biotechnology (Shanghai) Co., Ltd.Wei Ya Zhen Sheng Wu Ji Shu （ Su Zhou ） You Xian Gong SiVisirna Therapeutics HK Limited
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationBreakthrough Therapy (CN)
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Related

3
Clinical Trials associated with VSA-003
NCT05851066 / Not yet recruitingPhase 1
A Phase 1 Single Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Effects of VSA003 in Chinese Adult Healthy Volunteers
CTR20231369 / Not yet recruitingPhase 1
一项在中国健康成人志愿者中评价VSA003单次给药的安全性、耐受性、药代动力学和药效学的I期临床研究
[Translation] A Phase I clinical study evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of a single dose of VSA003 in healthy adult volunteers in China
CTR20244397 / Not yet recruitingPhase 3
一项在中国青少年和成人纯合子型家族性高胆固醇血症（HoFH）患者中评价VSA003注射液有效性和安全性的Ⅲ期临床研究
[Translation] A Phase III clinical study evaluating the efficacy and safety of VSA003 injection in Chinese adolescents and adults with homozygous familial hypercholesterolemia (HoFH)
100 Clinical Results associated with VSA-003
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100 Translational Medicine associated with VSA-003
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100 Patents (Medical) associated with VSA-003
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100 Deals associated with VSA-003
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Homozygous familial hypercholesterolemiaPhase 3
CN
Wei Ya Zhen Sheng Wu Ji Shu （ Su Zhou ） You Xian Gong Si
22 Nov 2024
DyslipidemiasPhase 2
CN
Visirna Biotechnology (Shanghai) Co., Ltd.
-
Hyperlipoproteinemia Type IIPhase 1-
Visirna Therapeutics HK Limited
01 Jun 2023
HypertriglyceridemiaPhase 1-
Visirna Therapeutics HK Limited
01 Jun 2023
Complex dyslipidemiaPhase 1
CN
Visirna Therapeutics HK Limited
10 May 2023
Primary hypercholesterolemiaPhase 1
CN
Visirna Therapeutics HK Limited
10 May 2023
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Clinical Result

Indication
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Evaluation
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Regulation

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