Last update 13 Dec 2025

AZD4248

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
NNMT
Action
inhibitors
Mechanism
NNMT inhibitors(nicotinamide N-methyltransferase inhibitors)
Therapeutic Areas
Endocrinology and Metabolic DiseaseUrogenital Diseases
Active Indication
Chronic Kidney DiseasesDiabetes Mellitus, Type 2
Inactive Indication-
Originator Organization
AstraZeneca PLCAstraZeneca PLC
Active Organization
AstraZeneca PLCAstraZeneca PLC
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with AZD4248
NCT07024823
/ RecruitingPhase 1
A Phase I Randomized, Single-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 Following Single and Multiple Ascending Dose Administration in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Prospective, Non-interventional Cohort Study
100 Clinical Results associated with AZD4248
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100 Translational Medicine associated with AZD4248
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100 Patents (Medical) associated with AZD4248
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100 Deals associated with AZD4248
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic Kidney DiseasesPhase 1
United States
AstraZeneca PLCAstraZeneca PLC
09 Jun 2025
Diabetes Mellitus, Type 2Phase 1
United States
AstraZeneca PLCAstraZeneca PLC
09 Jun 2025
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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