[Translation] A multicenter, open-label phase II clinical trial evaluating the efficacy and safety of BAT8008 in combination with BAT1308±BAT4706 in patients with advanced solid tumors.

研究主要目的：评估BAT8008联合BAT1308±BAT4706在晚期实体瘤患者中的安全性；评价BAT8008联合BAT1308±BAT4706的抗肿瘤疗效，为后续临床试验提供推荐剂量；研究次要目的：评价BAT8008联合BAT1308±BAT4706的免疫原性；探索BAT8008联合BAT1308±BAT4706抗肿瘤疗效与肿瘤组织PDL1、Trop2表达水平的关系；

[Translation]

Primary objectives: To evaluate the safety of BAT8008 combined with BAT1308±BAT4706 in patients with advanced solid tumors; to assess the antitumor efficacy of BAT8008 combined with BAT1308±BAT4706 and provide recommended dosage for subsequent clinical trials; Secondary objectives: To evaluate the immunogenicity of BAT8008 combined with BAT1308±BAT4706; to explore the relationship between the antitumor efficacy of BAT8008 combined with BAT1308±BAT4706 and the expression levels of PDL1 and Trop2 in tumor tissues;

Start Date19 Jun 2025

Sponsor / Collaborator

Bio-Thera Solutions, Ltd.

NCT06139536

/ Unknown statusPhase 1

A Phase 1, Multicenter, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BAT4706 Injection Combined With BAT1308 Injection in Patients With Advanced Solid Tumors

This is a Phase 1, Multicenter, Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BAT4706 Injection Combined With BAT1308 Injection in Patients With Advanced Solid Tumors.

Start Date06 Mar 2024

Sponsor / Collaborator

Bio-Thera Solutions, Ltd.

NCT05148325

/ CompletedPhase 1

A Phase I Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetics of BAT4706 Injection in Patients With Advanced Solid Tumors

A Phase I Clinical Study to Evaluate the Safety, Tolerance and Pharmacokinetics of BAT4706 Injection in Patients With Advanced Solid Tumors.

Start Date02 Sep 2021

Sponsor / Collaborator

Bio-Thera Solutions, Ltd.

100 Clinical Results associated with BAT-4706

100 Translational Medicine associated with BAT-4706

100 Patents (Medical) associated with BAT-4706

100 Deals associated with BAT-4706

R&D Status

10 top R&D records.

to view more data

Indication	Highest Phase	Country/Location	Organization	Date
Hepatocellular Carcinoma	Phase 1	China	Bio-Thera Solutions, Ltd.	06 Mar 2024
MSS/pMMR/MSI-L Colorectal Carcinoma	Phase 1	China	Bio-Thera Solutions, Ltd.	06 Mar 2024
Non-Small Cell Lung Cancer	Phase 1	China	Bio-Thera Solutions, Ltd.	06 Mar 2024
Advanced Malignant Solid Neoplasm	Phase 1	China	Bio-Thera Solutions, Ltd.	02 Sep 2021
Melanoma	Phase 1	China	Bio-Thera Solutions, Ltd.	02 Sep 2021

Clinical Result

Indication

Phase

Evaluation

View All Results

Translational Medicine

Boost your research with our translational medicine data.

view full example data

Deal

Boost your decision using our deal data.

view full example data

Core Patent

Boost your research with our Core Patent data.

view full example data

Clinical Trial

Identify the latest clinical trials across global registries.

view full example data

Approval

Accelerate your research with the latest regulatory approval information.

view full example data

Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

view full example data

Regulation

Understand key drug designations in just a few clicks with Synapse.

view full example data

AI Agents Built for Biopharma Breakthroughs

Accelerate discovery. Empower decisions. Transform outcomes.

Get started for free today!

Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.

Start your data trial now!

Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.

Bio

Bio Sequences Search & Analysis

Chemical

Chemical Structures Search & Analysis