Last update 24 May 2025

ADR+/CD58KO CAR iT cells(Fate)

Overview

Basic Info

Drug Type
Universal CAR-T, Induced pluripotent stem cells (iPSC)
Synonyms-
Target
4-1BB x BCMA x CD58
Action
agonists, inhibitors
Mechanism
4-1BB agonists(Tumor necrosis factor receptor superfamily member 9 agonists), BCMA inhibitors(B-cell maturation protein inhibitors), CD58 inhibitors(Lymphocyte function-associated antigen 3 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
LeukemiaLymphoma
Inactive Indication-
Originator Organization
Fate Therapeutics, Inc.Fate Therapeutics, Inc.
Active Organization
Fate Therapeutics, Inc.Fate Therapeutics, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with ADR+/CD58KO CAR iT cells(Fate)
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100 Translational Medicine associated with ADR+/CD58KO CAR iT cells(Fate)
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100 Patents (Medical) associated with ADR+/CD58KO CAR iT cells(Fate)
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100 Deals associated with ADR+/CD58KO CAR iT cells(Fate)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
LeukemiaPreclinical
United States
Fate Therapeutics, Inc.Fate Therapeutics, Inc.
08 Dec 2024
LymphomaPreclinical
United States
Fate Therapeutics, Inc.Fate Therapeutics, Inc.
08 Dec 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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