Last update 13 Sep 2025

RO-7673396

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
RG 6505, RG-6505, RG6505
+ [1]
Target
RAS
Action
inhibitors
Mechanism
RAS inhibitors(RAS type GTPase family inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Roche Holding AGRoche Holding AG
Active Organization
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.Roche R & D Center China Co. Ltd.Roche R & D Center China Co. Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with RO-7673396
NCT06884618
/ RecruitingPhase 1
A Phase I Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Clinical Activity of RO7673396 as a Single Agent and in Combination With Other Anticancer Therapies in Patients With Advanced Solid Tumors Harboring RAS Mutation(s)
100 Clinical Results associated with RO-7673396
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100 Translational Medicine associated with RO-7673396
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100 Patents (Medical) associated with RO-7673396
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100 Deals associated with RO-7673396
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
United States
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
30 Apr 2025
Advanced Malignant Solid NeoplasmPhase 1
China
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
30 Apr 2025
Advanced Malignant Solid NeoplasmPhase 1
Australia
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
30 Apr 2025
Advanced Malignant Solid NeoplasmPhase 1
Hong Kong
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
30 Apr 2025
Advanced Malignant Solid NeoplasmPhase 1
New Zealand
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
30 Apr 2025
Advanced Malignant Solid NeoplasmPhase 1
Singapore
Hoffmann-La Roche Ltd.Hoffmann-La Roche Ltd.
30 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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