Last update 20 Apr 2026

JNJ-88998377

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
JNJ-8377, JNJ8377, JNJ88998377
Target
MALT1 x TRPV1
Action
inhibitors, antagonists
Mechanism
MALT1 inhibitors(Mucosa-associated lymphoid tissue lymphoma translocation protein 1 inhibitors), TRPV1 antagonists(Transient receptor potential cation channel subfamily V member 1 antagonists)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [2]
Active Indication
B-Cell LymphomaB-cell lymphoma refractoryDiffuse large B-cell lymphoma recurrent+ [4]
Inactive Indication-
Originator Organization
Johnson & Johnson (China) Investment Ltd.Johnson & Johnson (China) Investment Ltd.
Active Organization
Janssen Research & Development LLCJohnson & Johnson (China) Investment Ltd.Johnson & Johnson (China) Investment Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
Login to view timeline

Related

1
Clinical Trials associated with JNJ-88998377
NCT06470438
/ Active, not recruitingPhase 1
A Phase 1, First-in-Human, Dose Escalation Study of JNJ-88998377 in Participants With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma (NHL)
100 Clinical Results associated with JNJ-88998377
Login to view more data
100 Translational Medicine associated with JNJ-88998377
Login to view more data
100 Patents (Medical) associated with JNJ-88998377
Login to view more data
100 Deals associated with JNJ-88998377
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
B-Cell LymphomaPhase 1
Japan
Johnson & Johnson (China) Investment Ltd.Johnson & Johnson (China) Investment Ltd.
28 May 2024
B-Cell LymphomaPhase 1
Italy
Johnson & Johnson (China) Investment Ltd.Johnson & Johnson (China) Investment Ltd.
28 May 2024
B-Cell LymphomaPhase 1
Poland
Johnson & Johnson (China) Investment Ltd.Johnson & Johnson (China) Investment Ltd.
28 May 2024
B-Cell LymphomaPhase 1
South Korea
Johnson & Johnson (China) Investment Ltd.Johnson & Johnson (China) Investment Ltd.
28 May 2024
B-Cell LymphomaPhase 1
Turkey
Johnson & Johnson (China) Investment Ltd.Johnson & Johnson (China) Investment Ltd.
28 May 2024
B-cell lymphoma refractoryPhase 1
China
Janssen Research & Development LLC
28 May 2024
B-cell lymphoma refractoryPhase 1
Japan
Janssen Research & Development LLC
28 May 2024
B-cell lymphoma refractoryPhase 1
Italy
Janssen Research & Development LLC
28 May 2024
B-cell lymphoma refractoryPhase 1
Poland
Janssen Research & Development LLC
28 May 2024
B-cell lymphoma refractoryPhase 1
South Korea
Janssen Research & Development LLC
28 May 2024
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free