Last update 14 Nov 2024

TY-0540

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TY-0540, TYK 00540, TYK-00540
+ [1]
Target
CDK2 x CDK4 x CDK6
Mechanism
CDK2 inhibitors(Cyclin-dependent kinase 2 inhibitors), CDK4 inhibitors(Cyclin-dependent kinase 4 inhibitors), CDK6 inhibitors(Cyclin-dependent kinase 6 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication
Advanced Malignant Solid NeoplasmBreast CancerPancreatic Cancer+ [1]
Inactive Indication-
Originator Organization
TYK Medicines, Inc.TYK Medicines, Inc.Startup
Active Organization
TYK Medicines, Inc.TYK Medicines, Inc.Startup
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with TY-0540
NCT06246071 / RecruitingPhase 1
A Phase Ia/Ib, Multicenter, Open-label Study of TYK-00540, Administered Orally in Adult Patients With Locally Advanced/Metastatic Solid Tumors
CTR20233663 / RecruitingPhase 1
一项评价CDK2/4/6抑制剂TYK-00540片在晚期实体瘤患者中安全性、耐受性、药代动力学及有效性的Ia/Ib期临床研究
[Translation] A Phase Ia/Ib clinical study evaluating the safety, tolerability, pharmacokinetics and efficacy of the CDK2/4/6 inhibitor TYK-00540 tablets in patients with advanced solid tumors
100 Clinical Results associated with TY-0540
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100 Translational Medicine associated with TY-0540
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100 Patents (Medical) associated with TY-0540
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100 Deals associated with TY-0540
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
CN
TYK Medicines, Inc.TYK Medicines, Inc.Startup
28 Dec 2023
Breast CancerIND Approval
CN
TYK Medicines, Inc.TYK Medicines, Inc.Startup
08 Sep 2023
Pancreatic CancerIND Approval
CN
TYK Medicines, Inc.TYK Medicines, Inc.Startup
08 Sep 2023
Prostatic CancerIND Approval
CN
TYK Medicines, Inc.TYK Medicines, Inc.Startup
08 Sep 2023
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Clinical Result

Indication
Phase
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Approval

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Regulation

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