Last update 10 Aug 2026

AB-103 (AevisBio)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AB103, AB103e, AB103i
Target
ZFP91 x α-synuclein
Action
degraders, inhibitors
Mechanism
ZFP91 degraders(Protein cereblon/E3 ubiquitin-protein ligase ZFP91 degraders), α-synuclein inhibitors(Synuclein alpha inhibitors)
Therapeutic Areas
Nervous System DiseasesCardiovascular DiseasesEndocrinology and Metabolic Disease+ [1]
Active Indication
Brain Injuries, TraumaticMultiple System AtrophyStroke+ [2]
Inactive Indication-
Originator Organization
AevisBio, Inc.AevisBio, Inc.
Active Organization
AevisBio, Inc.AevisBio, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with AB-103 (AevisBio)
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100 Translational Medicine associated with AB-103 (AevisBio)
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100 Patents (Medical) associated with AB-103 (AevisBio)
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100 Deals associated with AB-103 (AevisBio)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Brain Injuries, TraumaticPreclinical
United States
AevisBio, Inc.AevisBio, Inc.
01 Aug 2026
Multiple System AtrophyPreclinical
United States
AevisBio, Inc.AevisBio, Inc.
01 Aug 2026
StrokePreclinical
United States
AevisBio, Inc.AevisBio, Inc.
01 Aug 2026
Alzheimer DiseasePreclinical
United States
AevisBio, Inc.AevisBio, Inc.
15 May 2024
Parkinson DiseasePreclinical
United States
AevisBio, Inc.AevisBio, Inc.
15 May 2024
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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