Last update 18 Nov 2025

BMS-986463

Overview

Basic Info

Drug Type
Degradable Molecular Glue
Synonyms
WEE1 CELMoD, BMS 986463, BMS986463
Target
WEE1
Action
degraders
Mechanism
WEE1 degraders(Serine/threonine-protein kinase WEE1 degraders)
Therapeutic Areas
NeoplasmsRespiratory DiseasesUrogenital Diseases
Active Indication
Advanced cancerhigh grade serous adenocarcinoma of ovaryNon-Small Cell Lung Cancer+ [1]
Inactive Indication-
Originator Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Active Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Inactive Organization-
License Organization
Evotec SEEvotec SEBristol Myers Squibb Co.Bristol Myers Squibb Co.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC32H33FN4O5
InChIKeyJPTNRZBZSUZXCS-CUBQBAPOSA-N
CAS Registry3025467-07-3

Related

1
Clinical Trials associated with BMS-986463
NCT06476808
/ RecruitingPhase 1
A Phase 1/1b First-in-human Study of BMS-986463 in Advanced Malignant Tumors
100 Clinical Results associated with BMS-986463
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100 Translational Medicine associated with BMS-986463
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100 Patents (Medical) associated with BMS-986463
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100 Deals associated with BMS-986463
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced cancerPhase 1
United States
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
Advanced cancerPhase 1
Canada
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
Advanced cancerPhase 1
France
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
Advanced cancerPhase 1
Italy
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
Advanced cancerPhase 1
Spain
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
high grade serous adenocarcinoma of ovaryPhase 1
United States
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
high grade serous adenocarcinoma of ovaryPhase 1
Canada
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
high grade serous adenocarcinoma of ovaryPhase 1
France
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
high grade serous adenocarcinoma of ovaryPhase 1
Italy
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
high grade serous adenocarcinoma of ovaryPhase 1
Spain
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
06 Sep 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Regulation

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