Last update 19 Mar 2026

Histrelin Acetate

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
[(im-Bzl)-D-His6,Pro9-NEt]-gonadotropin releasing hormone, Histrelin, Histrelin implant
+ [11]
Target
Action
agonists
Mechanism
GnRHR agonists(Gonadotropin-releasing hormone receptor agonists)
Active Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
United States (24 Dec 1991),
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC68H90N18O14
InChIKeyOWAUGAMNPZHEOJ-YKZVIGSYSA-N
CAS Registry220810-26-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Prostatic Cancer
United States
24 Dec 1991
Puberty, Precocious
United States
24 Dec 1991
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Adenocarcinoma of prostatePhase 3-01 Apr 2000
Advanced Prostate CarcinomaPhase 3-01 Apr 2000
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
36
Histrelin implant therapy
okaefxzkrb(vzitvxigrb) = nkeojbahtn bfptjneqnp (pphjtneolx )
-
02 Dec 2013
Phase 3
134
Histrelin acetate 50 mg subdermal implant
kgbihwtgiu(zeppxcrhex) = qkndstdmxm epscypzubh (zdpbogcglz )
Positive
01 Apr 2006
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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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