Delving into the Latest Updates on TYF-IL-2Rg gene-modified autologous stem cells(Shenzhen Geno-Immune Medical Institute) with Synapse

Overview

Basic Info

Drug Type

Gene therapy, Hematopoietic stem cell therapy

Synonyms-

Target

IL-2Rγ

Mechanism

IL-2Rγ stimulants(Interleukin-2 receptor subunit gamma stimulants)

Therapeutic Areas

Immune System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [1]

Active Indication

X-Linked Combined Immunodeficiency Diseases

Inactive Indication-

Originator Organization

Shenzhen Geno-Immune Medical Institute

Active Organization

Shenzhen Geno-Immune Medical Institute

Inactive Organization-

Drug Highest PhasePhase 1/2

First Approval Date-

Regulation-

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This is a Phase I/II gene therapy trial treating X-linked severe combined immunodeficiency (SCID-X1) using a self-inactivating lentiviral vector (ivlv-X1) to functionally correct the genetic defect. The primary objectives are to evaluate the safety and efficacy of the direct intravenous lentiviral gene transfer protocol.

Start Date30 Jun 2024

Sponsor / Collaborator

Shenzhen Geno-Immune Medical Institute

NCT03645486

/ Unknown statusNot ApplicableIIT

Lentiviral Gene Therapy for Chronic Granulomatous Disease (CGD)

This is a Phase I/II clinical trial of gene therapy for treating Chronic Granulomatous Disease using a high-safety, high-efficiency, self-inactivating lentiviral vector TYF to functionally correct the defective gene. The objectives are to evaluate the safety and efficacy of the TYF-CGD gene transfer clinical protocol.

Start Date01 Jul 2018

Sponsor / Collaborator

Shenzhen Geno-Immune Medical Institute

100 Clinical Results associated with TYF-IL-2Rg gene-modified autologous stem cells(Shenzhen Geno-Immune Medical Institute)

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100 Translational Medicine associated with TYF-IL-2Rg gene-modified autologous stem cells(Shenzhen Geno-Immune Medical Institute)

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100 Patents (Medical) associated with TYF-IL-2Rg gene-modified autologous stem cells(Shenzhen Geno-Immune Medical Institute)

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100 Deals associated with TYF-IL-2Rg gene-modified autologous stem cells(Shenzhen Geno-Immune Medical Institute)

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