Last update 22 Dec 2024

GYKI-12743

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
GYKI 12743
Target
α-adrenergic receptor
Mechanism
α-adrenergic receptor antagonists(Alpha adrenergic receptor antagonists)
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
Hypertension
Originator Organization
Chemical Works of Gedeon Richter PlcChemical Works of Gedeon Richter Plc
Active Organization-
Inactive Organization
Gedeon Richter Pharma GmbHChemical Works of Gedeon Richter PlcChemical Works of Gedeon Richter Plc
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure

Molecular FormulaC16H20ClN3O3
InChIKeyWJDFSAOMSJHHCG-UHFFFAOYSA-N
CAS Registry110714-10-8

Related

100 Clinical Results associated with GYKI-12743
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100 Translational Medicine associated with GYKI-12743
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100 Patents (Medical) associated with GYKI-12743
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6
Literatures (Medical) associated with GYKI-12743
01 Jan 1994Acta physiologica Hungarica
Demonstration of the potassium channel opening activity of GYKI-12743 by 86Rb+ efflux studies.
01 Jan 1991Acta physiologica Hungarica
GYKI-12743 a new postsynaptic vascular alpha-adrenoceptor antagonist.
01 Jan 1990Acta physiologica Hungarica
Study of the predominant vascular postsynaptic alpha-adrenergic blocking capacity of GYKI-12 743 in isolated organs and pithed rats.
100 Deals associated with GYKI-12743
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HypertensionPhase 1
HU
Gedeon Richter Pharma GmbH
-
HypertensionPhase 1-
Chemical Works of Gedeon Richter PlcChemical Works of Gedeon Richter Plc
-
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Clinical Result

Indication
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Approval

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Regulation

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