Last update 29 Nov 2025

SPGL008

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
SPGL008
Target
CD276 x IL-15
Action
modulators
Mechanism
CD276 modulators(CD276 antigen modulators), IL-15 modulators(Interleukin-15 modulators)
Therapeutic Areas
Neoplasms
Active Indication
Neoplasm MetastasisAdvanced Malignant Solid NeoplasmAdvanced cancer
Inactive Indication-
Originator Organization
Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.
Active Organization
Shenyang Sunshine Pharmaceuticals Co., Ltd.Shenyang Sunshine Pharmaceuticals Co., Ltd.Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with SPGL008
NCT07038005
/ Not yet recruitingPhase 1
A Phase I Clinical Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of SPGL008 Monotherapy for Patients With Advanced Malignant Tumors
100 Clinical Results associated with SPGL008
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100 Translational Medicine associated with SPGL008
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100 Patents (Medical) associated with SPGL008
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100 Deals associated with SPGL008
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Neoplasm MetastasisPhase 1-
Shenyang Sunshine Pharmaceuticals Co., Ltd.Shenyang Sunshine Pharmaceuticals Co., Ltd.
13 Jul 2025
Neoplasm MetastasisPhase 1-
Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.
13 Jul 2025
Advanced Malignant Solid NeoplasmPhase 1
China
Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.
30 Jun 2025
Advanced cancerIND Approval
China
Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.Shenzhen Sciprogen Bio-Pharmaceutical Co., Ltd.
26 May 2025
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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