Last update 01 Nov 2024

YK-2168

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
CDK9
Mechanism
CDK9 inhibitors(Cyclin-dependent kinase 9 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication
Advanced Malignant Solid NeoplasmNon-Hodgkin Lymphoma
Inactive Indication-
Originator Organization
Nanjing Damei Biopharmaceutical Co., Ltd.
Active Organization
Nanjing YOKO Pharmaceutical Co., Ltd.Nanjing YOKO Pharmaceutical Co., Ltd.Nanjing Damei Biopharmaceutical Co., Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with YK-2168
CTR20212900 / Active, not recruitingPhase 1
评价CDK9抑制剂YK-2168治疗晚期实体瘤以及淋巴瘤患者的安全性、耐受性、药代动力学特征及初步疗效的I/IIa期临床试验
[Translation] A phase I/IIa clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of CDK9 inhibitor YK-2168 in the treatment of patients with advanced solid tumors and lymphomas
100 Clinical Results associated with YK-2168
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100 Translational Medicine associated with YK-2168
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100 Patents (Medical) associated with YK-2168
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1
Literatures (Medical) associated with YK-2168
01 Nov 2024Bioorganic & Medicinal Chemistry Letters
Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development
100 Deals associated with YK-2168
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
CN
Nanjing YOKO Pharmaceutical Co., Ltd.Nanjing YOKO Pharmaceutical Co., Ltd.
19 Jan 2022
Advanced Malignant Solid NeoplasmPhase 1
CN
Nanjing Damei Biopharmaceutical Co., Ltd.
19 Jan 2022
Non-Hodgkin LymphomaPhase 1
CN
Nanjing Damei Biopharmaceutical Co., Ltd.
19 Jan 2022
Non-Hodgkin LymphomaPhase 1
CN
Nanjing YOKO Pharmaceutical Co., Ltd.Nanjing YOKO Pharmaceutical Co., Ltd.
19 Jan 2022
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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