Last update 08 May 2025

CXCR4 Modified CD19 CAR-T (Sichuan University)

Overview

Basic Info

Drug Type
CAR-T
Synonyms-
Target
CD19 x CXCR4
Action
inhibitors, antagonists
Mechanism
CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors), CXCR4 antagonists(C-X-C motif chemokine receptor 4 antagonists)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
B-cell lymphoma refractoryRefractory Leukemia
Originator Organization
Sichuan UniversitySichuan University
Active Organization-
Inactive Organization
Sichuan UniversitySichuan University
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CXCR4 Modified CD19 CAR-T (Sichuan University)
NCT04684472
/ Unknown statusPhase 1IIT
Phase I, Open Label, Study of CXCR4 Modified CD19 CAR-T Therapy in Patients With Relapsed or Refractory CD19+ B-cell Malignancies
100 Clinical Results associated with CXCR4 Modified CD19 CAR-T (Sichuan University)
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100 Translational Medicine associated with CXCR4 Modified CD19 CAR-T (Sichuan University)
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100 Patents (Medical) associated with CXCR4 Modified CD19 CAR-T (Sichuan University)
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100 Deals associated with CXCR4 Modified CD19 CAR-T (Sichuan University)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
B-cell lymphoma refractoryPhase 1
China
Sichuan UniversitySichuan University
17 Mar 2021
Refractory LeukemiaPhase 1
China
Sichuan UniversitySichuan University
17 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Clinical Trial

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Approval

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Regulation

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