Last update 12 Apr 2025

TOP-V122

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
TOP V122, TOP-V-122
Target
PDE5A
Action
inhibitors, donors
Mechanism
PDE5A inhibitors(Phosphodiesterase 5A inhibitors), Nitric oxide donors
Therapeutic Areas
NeoplasmsImmune System DiseasesCardiovascular Diseases+ [6]
Active Indication
Colorectal CancerDiabetic RetinopathyDystrophy, Macular+ [3]
Inactive Indication-
Originator Organization
Topadur Pharma AGTopadur Pharma AGStartup
Active Organization
UniversitätsSpital ZürichUniversitätsSpital ZürichTopadur Pharma AGTopadur Pharma AGStartupUniversity of ZurichUniversity of Zurich
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with TOP-V122
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100 Translational Medicine associated with TOP-V122
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100 Patents (Medical) associated with TOP-V122
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100 Deals associated with TOP-V122
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPreclinical
Switzerland
UniversitätsSpital ZürichUniversitätsSpital Zürich
-
Colorectal CancerPreclinical
Switzerland
University of ZurichUniversity of Zurich
-
Colorectal CancerPreclinical
Switzerland
Topadur Pharma AGTopadur Pharma AGStartup
-
Diabetic RetinopathyPreclinical
Switzerland
Topadur Pharma AGTopadur Pharma AGStartup
-
Dystrophy, MacularPreclinical
Switzerland
Topadur Pharma AGTopadur Pharma AGStartup
-
Idiopathic Pulmonary FibrosisPreclinical
Switzerland
Topadur Pharma AGTopadur Pharma AGStartup
-
Inflammatory Bowel DiseasesPreclinical
Switzerland
Topadur Pharma AGTopadur Pharma AGStartup
-
Pulmonary Arterial HypertensionPreclinical
Switzerland
Topadur Pharma AGTopadur Pharma AGStartup
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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