Last update 24 May 2025

LCAR-AMDR Cells(Nanjing Legend Biotech Co.)

Overview

Basic Info

Drug Type
Universal CAR-T
Synonyms-
Target
CD33 x CLL-1
Action
modulators
Mechanism
CD33 modulators(Myeloid cell surface antigen CD33 modulators), CLL-1 modulators(C-Type lectin domain family 12 member A modulators), Immunologic cytotoxicity
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
Refractory acute myeloid leukemiaRelapsing acute myeloid leukemia
Originator Organization
Nanjing Legend Biotech Co., Ltd.Nanjing Legend Biotech Co., Ltd.
Active Organization-
Inactive Organization
Nanjing Legend Biotech Co., Ltd.Nanjing Legend Biotech Co., Ltd.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with LCAR-AMDR Cells(Nanjing Legend Biotech Co.)
NCT05654779
/ TerminatedPhase 1IIT
A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of CLL1-/CD33 Targeted LCAR-AMDR Cells Product in Patients With Relapsed/Refractory Acute Myeloid Leukemia
100 Clinical Results associated with LCAR-AMDR Cells(Nanjing Legend Biotech Co.)
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100 Translational Medicine associated with LCAR-AMDR Cells(Nanjing Legend Biotech Co.)
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100 Patents (Medical) associated with LCAR-AMDR Cells(Nanjing Legend Biotech Co.)
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100 Deals associated with LCAR-AMDR Cells(Nanjing Legend Biotech Co.)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Refractory acute myeloid leukemiaPhase 1
China
Nanjing Legend Biotech Co., Ltd.Nanjing Legend Biotech Co., Ltd.
12 Dec 2022
Relapsing acute myeloid leukemiaPhase 1
China
Nanjing Legend Biotech Co., Ltd.Nanjing Legend Biotech Co., Ltd.
12 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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