Delving into the Latest Updates on Vitamin B6/Cyanocobalamin/Vitamin B1 with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms-

Target

MUT

Action

stimulants

Mechanism

MUT stimulants(Methylmalonyl-CoA Mutase stimulants), Vitamin B1 supplements

Therapeutic Areas

Endocrinology and Metabolic Disease

Active Indication

Thiamine DeficiencyVitamin B 12 DeficiencyVitamin B 6 Deficiency

Inactive Indication-

Originator Organization-

Active Organization-

Inactive Organization-

License Organization-

Drug Highest PhaseApproved

First Approval Date-

Regulation-

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Structure/Sequence

Molecular FormulaC12H18Cl2N4OS

InChIKeyDPJRMOMPQZCRJU-UHFFFAOYSA-M

CAS Registry67-03-8

View All Structures (3)

This phase II trial studies how well levocarnitine and vitamin B complex works in treating abnormal high liver enzyme levels (hyperbilirubinemia) caused by treatment with PEG-asparaginase or inotuzumab ozogamicin in patients with acute lymphoblastic leukemia. Amino acids, such as levocarnitine, may work in normalizing liver enzyme levels due to treatment. Vitamin B complex is a dietary supplement that may be used for patients with nutritional deficiencies. Giving levocarnitine and vitamin B complex may work better in treating hyperbilirubinemia in patients with acute lymphoblastic leukemia.

Start Date17 May 2018

Sponsor / Collaborator