Last update 08 May 2025

[(11)C]ADX88178

Overview

Basic Info

Drug Type
Diagnostic radiopharmaceuticals, Radionuclide Drug Conjugates (RDC)
Synonyms
Target
mGluR4
Action-
Mechanism
mGluR4 positive allosteric modulators(Metabotropic glutamate receptor 4 positive allosteric modulators)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
National Institute of Radiological SciencesNational Institute of Radiological Sciences
Active Organization-
Inactive Organization
National Institute of Radiological SciencesNational Institute of Radiological Sciences
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC12H12N6S
InChIKeyMIQNXKWDQRNHAU-BJUDXGSMSA-N
CAS Registry1849004-50-7
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Related

100 Clinical Results associated with [(11)C]ADX88178
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100 Translational Medicine associated with [(11)C]ADX88178
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100 Patents (Medical) associated with [(11)C]ADX88178
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1
Literatures (Medical) associated with [(11)C]ADX88178
01 Jan 2016Bioorganic & Medicinal Chemistry LettersQ4 · MEDICINE
Radiosynthesis and evaluation of 5-methyl- N -(4-[ 11 C]methylpyrimidin-2-yl)-4-(1 H -pyrazol-4-yl)thiazol-2-amine ([ 11 C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4)
Q4 · MEDICINE
100 Deals associated with [(11)C]ADX88178
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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