Last update 11 Jul 2025

dTAG-63

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
dTAG-63
Target
FKBP1A
Action
inhibitors, degraders
Mechanism
FKBP12 inhibitors(FK506-binding protein 1A inhibitors), FKBP1A degraders(FK506-binding protein 1A degraders)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.Harvard Medical SchoolHarvard Medical School
Active Organization-
Inactive Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.Harvard Medical SchoolHarvard Medical School
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC69H92N6O17S
InChIKeyQTSHFYXEXAHVCR-DBYQZFFGSA-N
CAS Registry-

Related

100 Clinical Results associated with dTAG-63
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100 Translational Medicine associated with dTAG-63
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100 Patents (Medical) associated with dTAG-63
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100 Deals associated with dTAG-63
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
Harvard Medical SchoolHarvard Medical School
18 Sep 2020
NeoplasmsPreclinical
United States
Novartis Institutes for Biomedical Research, Inc.Novartis Institutes for Biomedical Research, Inc.
18 Sep 2020
NeoplasmsPreclinical
United States
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
18 Sep 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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