Last update 16 May 2025

HJ-891

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
HJ 891, HJ-891, HJ891
Target-
Action-
Mechanism-
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
Non-Small Cell Lung CancerKRAS G12C mutant non-squamous non-small cell lung cancerAdvanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Chengdu Huajian Future Technology Co., LtdChengdu Huajian Future Technology Co., Ltd
Active Organization
Chengdu Huajian Future Technology Co., LtdChengdu Huajian Future Technology Co., Ltd
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

4
Clinical Trials associated with HJ-891
CTR20251444
/ Not yet recruitingPhase 1
HJ891 胶囊在中国健康成人受试者中的随机、开放、两周期、双交叉食物影响研究
[Translation] A randomized, open-label, two-period, double-crossover food-effect study of HJ891 capsules in healthy Chinese adult subjects
CTR20231351
/ Not yet recruitingPhase 2
评价 HJ891 用于非小细胞肺癌的抗肿瘤疗效的单臂、开放 IIb 期临床研究
[Translation] A single-arm, open-label phase IIb clinical study to evaluate the anti-tumor efficacy of HJ891 in non-small cell lung cancer
CTR20212195
/ Not yet recruitingPhase 1
评价HJ891治疗晚期实体瘤的安全性、耐受性、药代动力学及抗肿瘤疗效的单臂、开放I期临床研究
[Translation] A single-arm, open-label phase I clinical study to evaluate the safety, tolerability, pharmacokinetics and anti-tumor efficacy of HJ891 in the treatment of advanced solid tumors
100 Clinical Results associated with HJ-891
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100 Translational Medicine associated with HJ-891
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100 Patents (Medical) associated with HJ-891
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100 Deals associated with HJ-891
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 2
China
Chengdu Huajian Future Technology Co., LtdChengdu Huajian Future Technology Co., Ltd
04 May 2023
KRAS G12C mutant non-squamous non-small cell lung cancerPhase 1
China
Chengdu Huajian Future Technology Co., LtdChengdu Huajian Future Technology Co., Ltd
08 Jan 2024
Advanced Malignant Solid NeoplasmPhase 1
China
Chengdu Huajian Future Technology Co., LtdChengdu Huajian Future Technology Co., Ltd
03 Sep 2021
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Clinical Result

Indication
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Approval

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Regulation

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