[Translation] A randomized, double-blind, placebo-controlled phase I clinical trial evaluating the safety, tolerability, pharmacodynamics, and effects of administration route of AP-2202 tablets in healthy adult participants in China using single- or multiple-dose escalation methods.
主要目的:
评估AP-2202片在中国健康参与者中单、多次口服给药后的安全性和耐受性;
次要目的:
评估AP-2202片在中国健康参与者中单、多次口服给药后的药效动力学(PD)特征;
评估不同服药方式(餐前1h 服用、随餐服用)对AP-2202 片在中国健康参与者中药效动力学的影响;
[Translation] Primary objective: To evaluate the safety and tolerability of AP-2202 tablets after single and multiple oral administration in healthy Chinese participants;
Secondary objective: To evaluate the pharmacodynamic (PD) characteristics of AP-2202 tablets after single and multiple oral administration in healthy Chinese participants;
To evaluate the effects of different administration methods (1 hour before meals or with meals) on the pharmacodynamics of AP-2202 tablets in healthy Chinese participants;