Last update 17 Jul 2025

ZXH-4-137

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms-
Target
CRBN
Action
degraders
Mechanism
CRBN degraders(Cereblon degraders), Proteolysis
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Harvard Medical SchoolHarvard Medical School
Active Organization-
Inactive Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.Harvard Medical SchoolHarvard Medical School
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC47H60N6O9S
InChIKeyUGUKTSSDXKQLTH-KBUFTDGKSA-N
CAS Registry2711006-74-3

Related

100 Clinical Results associated with ZXH-4-137
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100 Translational Medicine associated with ZXH-4-137
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100 Patents (Medical) associated with ZXH-4-137
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1
Literatures (Medical) associated with ZXH-4-137
RSC medicinal chemistryQ4 · MEDICINE
Selective degradation-inducing probes for studying cereblon (CRBN) biology
Q4 · MEDICINE
100 Deals associated with ZXH-4-137
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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