Last update 16 Jan 2025

Acyclovir/Hydrocortisone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Xerclear
Target
DNA-directed DNA polymerase x GR
Mechanism
DNA-directed DNA polymerase inhibitors, GR agonists(Glucocorticoid receptor agonists)
Therapeutic Areas
Infectious DiseasesMouth and Tooth DiseasesSkin and Musculoskeletal Diseases
Active Indication
Herpes Labialis
Inactive Indication-
Originator Organization
Bausch Health US LLC
Active Organization
Bausch Health US LLCMedivir ABMedivir ABHaleon Belgium NV
Inactive Organization
Daewoong Pharmaceutical Co., Ltd.Daewoong Pharmaceutical Co., Ltd.
Drug Highest PhaseApproved
First Approval Date
US (31 Jul 2009),
Herpes Labialis
Regulation-
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Structure/Sequence

Molecular FormulaC29H41N5O8
InChIKeyMDCGTBRYRLWFJI-WDCKKOMHSA-N
CAS Registry439279-66-0

Related

6
Clinical Trials associated with Acyclovir/Hydrocortisone
NCT01574612
/ CompletedPhase 3
An Open Label Multi Center Phase III Subject/Caregiver Initiated Safety Study of Xerese(Acyclovir and Hydrocortisone)Cream 5%/1% in the Treatment of Recurrent Herpes Labialis in Children
NCT00735761
/ CompletedPhase 3
A Randomized, Double-Blind, Active-Controlled, Subject Initiated Study Comparing ME-609 to Acyclovir Cream for Treatment of Recurrent Herpes Simplex Labialis in Immunocompromised Patients
EUCTR2006-002828-42-SE
/ Not yet recruitingNot Applicable
An open label, multi-centre, phase III, subject initiated safety study of ME-609 in treatment of recurrent herpes simplex labialis in adolescents.
100 Clinical Results associated with Acyclovir/Hydrocortisone
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100 Translational Medicine associated with Acyclovir/Hydrocortisone
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100 Patents (Medical) associated with Acyclovir/Hydrocortisone
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100 Deals associated with Acyclovir/Hydrocortisone
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External Link

KEGGWikiATCDrug Bank
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D06BB53
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Herpes Labialis
US
Bausch Health US LLC
31 Jul 2009
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Approval

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Regulation

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