Last update 21 Jun 2025

CD45RA-depleted peripheral blood mononuclear cells(Federal Research Institute of Pediatric Hematology, Oncology and Immunology)

Overview

Basic Info

Drug Type
Cell therapy
Synonyms-
Target-
Action-
Mechanism-
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication-
Inactive Indication
Acute Myeloid LeukemiaBone Marrow Failure DisordersGraft vs Host Disease+ [2]
Originator Organization
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Active Organization-
Inactive Organization
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
License Organization-
Drug Highest PhasePendingPhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CD45RA-depleted peripheral blood mononuclear cells(Federal Research Institute of Pediatric Hematology, Oncology and Immunology)
NCT02337595
/ CompletedPhase 1/2IIT
Transfusion of CD45RA-depleted Donor Lymphocytes to Improve Regeneration of Antimicrobial Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation
100 Clinical Results associated with CD45RA-depleted peripheral blood mononuclear cells(Federal Research Institute of Pediatric Hematology, Oncology and Immunology)
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100 Translational Medicine associated with CD45RA-depleted peripheral blood mononuclear cells(Federal Research Institute of Pediatric Hematology, Oncology and Immunology)
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100 Patents (Medical) associated with CD45RA-depleted peripheral blood mononuclear cells(Federal Research Institute of Pediatric Hematology, Oncology and Immunology)
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100 Deals associated with CD45RA-depleted peripheral blood mononuclear cells(Federal Research Institute of Pediatric Hematology, Oncology and Immunology)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 2
Russia
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
01 Aug 2014
Bone Marrow Failure DisordersPhase 2
Russia
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
01 Aug 2014
Graft vs Host DiseasePhase 2
Russia
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
01 Aug 2014
Immune Deficiency DiseasePhase 2
Russia
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
01 Aug 2014
Precursor T-Cell Lymphoblastic Leukemia-LymphomaPhase 2
Russia
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
01 Aug 2014
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Clinical Result

Indication
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Clinical Trial

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Approval

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Regulation

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