Einfluss Des süßmodulierenden Polyphenols Hesperetin in Kombination Mit Saccharose Auf Die Blutglukose-Regulierung Und Energieaufnahme in Abhängigkeit Der Süßwahrnehmung Teil 2

The aim of this cross-over intervention study is to investigate the influence of hesperetin applied in combination with sucrose in comparison to an equally sweet-tasting sucrose-only solution and an isocaloric sucrose-only solution on markers of energy metabolism

Start Date31 Mar 2024

Sponsor / Collaborator

University of Vienna

NCT06107231 / RecruitingNot Applicable

WHNRC (Western Human Nutrition Research Center) Honey Study

The purpose of this research is to compare two snacks, one with honey and nuts and the other with sugar and nuts, on glucose levels before and after eating these snacks.
The investigators hypothesize that honey and nuts will have an additive effect on the reduction of postprandial glucose response. The investigators further hypothesize that consumption of honey paired with nuts will retain the benefit of sugar consumption in satiety and reduction of metabolic stress.

Start Date16 Jan 2024

Sponsor / Collaborator

National Honey Board

100 Clinical Results associated with Sucrose

100 Translational Medicine associated with Sucrose

100 Patents (Medical) associated with Sucrose

6,102

Literatures (Medical) associated with Sucrose

01 Jun 2024·Food chemistry

The effects of dextran in residual impurity on trehalose crystallization and formula in food preservation

Article

Author: Cai, Jingwei ; Chen, Mingyang ; Li, Mingxuan ; Han, Dandan ; Zhang, Mengdi ; Peng, Ronghua ; Zhao, Wei ; Li, Jiahui ; Gong, Junbo ; Zhang, Leida ; Qin, Xueyou

The residual dextran impurities in the upstream process significantly impact the crystallization of starch-based functional sugar and the related food properties. This study intends to reveal the mechanism of dextran's influence on trehalose crystallization, and build a relationship among the dextran in syrup and the physicochemical and functional properties of trehalose. Instead of incorporating into the crystal lattice, dextran changes the assembly rate of trehalose molecules on crystal surface. The different sensitivity and adsorption capacity of the crystal surface to the chain length of dextran determines the growth rate of crystal surfaces, resulting in different crystal morphology. The bulk trehalose crystals, which were obtained from syrups with short chain dextran, have excellent powder properties, including best flowability (35^◦), highest crystal strength (2.7 N), lowest caking rate (62.22 %), and the most uniform mixing with other sweeteners (sucrose/xylitol) in food formulations, achieving more stable starch preservation.

01 May 2024·Food chemistry

The influence of γ-PGA on the quality of cooked frozen crayfish during temperature fluctuations

Article

Author: Abdelnaby, Taher ; Xue, Changhu ; Li, Zhaojie

The purpose of this study was to compare the influences of gamma-poly glutamic acid (γ-PGA) (1, 2, 3, and 4 %) to see which could outperform conventional cryoprotectant mixture (4 % sorbitol + 4 % sucrose) on cooked crayfish properties, such as physicochemical, textural qualities, oxidation reaction, water distributions, and microstructure integrity, during different freeze-thaw cycles. Crayfish quality characteristics improved significantly as γ-PGA concentration increased compared to control samples.Adding γ-PGA 4 % reduced the carbonyl content from 4.20 to 3.00 nmol/ mg protein during fluctuation-1 (F1), and from 4.15 to 2.80 nmol/ mg protein during fluctuation-2 (F2) compared to control samples. Furthermore, it increased the total sulfhydryl content from 4.15 and 4.76 to 6.19 and 6.47 mol/10⁵ g protein during F1 and F2 and after five freeze-thaw cycles (FTC). This suggests that this concentration was more effective at controlling protein changes than other concentrations. γ-PGA generally enhanced the water-holding capacity by preventing protein denaturation and limiting ice crystal recrystallization. As a result, microstructure stability was evident, texture degradation was avoided, and the crayfish's color was preserved.

01 May 2024·Food chemistry

Foam and fluid properties of purified saponins and non-purified water extracts from Camellia oleifera cake (by-product)

Article

Author: Zhu, Liwei ; Li, Pengfei ; Jiang, Jianxin ; Zhang, Weiwei ; Han, Chunrui ; Li, Weixin

The physicochemical and foam properties of non-purified water extracts (WE) and purified tea saponins (TS) from Camellia oleifera cake (byproduct) were compared. WE showed different fluid properties at equal saponin concentrations (1.0 wt%) compared to TS. Particularly, it exhibited limited micelle size (average 434.1 nm), effective viscosity (0.15 Pa·s), and surface tension (43.9 mN/m) independently of pH. Moreover, the foam properties of WE were comparable to TS and better than sodium caseinate, especially foam stability. WE foam was more stable than TS foam under pH (3-7) and heating (40-80 °C). In the presence of NaCl, sucrose, and ethanol (5-20 wt%), WE and TS were effective and had similar foam behavior. Low concentrations of sucrose (<10 wt%)/ethanol (<20 wt%) significantly increased the foam capacity, while ethanol over 30 wt% was unfavorable. WE/TS foam contributes significantly to the desired physicochemical and sensory attributes (taste, texture, and appearance) of foods.

News (Medical) associated with Sucrose

11 Mar 2024

·www.prnewswire.com

Tagatose Becomes First Sweetener and Ingredient to Earn NutraStrong™ Prebiotic Verified Certification

WEST PALM BEACH, Fla., March 11, 2024 /PRNewswire/ -- Tagatose, a monosaccharide that has gained popularity for its ability to meet calorie-reduction targets without compromising taste, texture or function, is now the first sweetener to attain the NutraStrong™ Prebiotic Verified certification. Continue Reading Tagatose Bonumose, Inc., a producer of tagatose, and ASR Group, its distributor, are proud to announce that tagatose is also the first ingredient to earn this prebiotic certification. This independent endorsement further establishes tagatose as an ideal ingredient for food, beverage and nutraceutical manufacturers seeking sweetener solutions that meet consumer demand for functional, lower-calorie products. As the global appetite for improved gut health continues to grow, demand for prebiotics is increasing because of the important role they play in nourishing beneficial gut bacteria and promoting digestive health. In fact, according to Innova Market Insights, new product launches featuring prebiotic ingredients enjoyed a 6% CAGR between 2017-2023. "Today's consumers want their foods and beverages to work harder for them, so it's no surprise they're seeking prebiotic ingredients," said Karen Weikel, Ph.D., Director of Nutrition Science at Bonumose. "Tagatose is a revolutionary product, because for the first time, we can offer manufacturers a sweetener solution that provides prebiotic benefits, while maintaining the sweetness consumers desire." NutraStrong™ Prebiotic Verified is an industry-spanning program that classifies products with relevant and specific standards for each product category. These standards set a baseline of quality and testing to ensure the market is providing customers with quality prebiotic products. "Bonumose's commitment to both the quality and science required for prebiotic certification serve as an example for the industry," said Kevin Yan, Vice President of Certifications and Analytics at SGS Nutrasource, the company that administers NutraStrong™ certification. "By becoming a certified ingredient, Bonumose gained access to the Prebiotic Certified program for all products utilizing their tagatose. This access gives brands the ability to certify and promote their own usage of tagatose, highlighting the benefits of such quality ingredients." "When the Global Prebiotic Association conceived of the Prebiotic Verified program as part of the NutraStrong™ umbrella, it was to create a reward for suppliers and brands with substantiated prebiotic products - those that invested in quality and science and those that formulated wisely," said Len Monheit, Executive Director of the Global Prebiotic Association. "We are truly excited that the inaugural ingredient through the program is tagatose and that the NutraStrong™ Prebiotic Verified program now includes an ingredient that brands can leverage." Tagatose's prebiotic properties are just one of the many benefits it provides to manufacturers. Compared to sucrose, tagatose is 90% as sweet with 60% fewer calories. It tastes and performs similar to sucrose across a wide variety of applications. Because it has a low glycemic index of 3, tagatose does not raise blood glucose levels when consumed on its own. It is also Ketogenic Certified, Non-GMO Project Verified and Plant-Based Certified. "We believe it's important to provide manufacturers with a variety of sweeteners to meet all of their needs," said Jim Kappas, Vice President of Specialty Ingredients at ASR Group. "Tagatose is a fitting solution for manufacturers who seek to make every calorie count with ingredients that taste great and provide functional benefits." ASR Group will be exhibiting at Natural Products Expo West 2024, March 13-16 in Anaheim, Calif. Attendees interested in learning more about the benefits of tagatose and sampling gummies made with tagatose can visit ASR Group at booth #1013. To learn more about tagatose, visit . Customers may request tagatose samples via this online form. Please contact Lisa Ptak at [email protected] to schedule appointments with ASR Group at Natural Products Expo West. About ASR Group ASR Group International, Inc. (ASR Group) is the world's largest refiner and marketer of cane sugar, with an annual production capacity of more than 6 million tons of sugar. The company produces a full line of grocery, industrial, food service and specialty sweetener products. Across North America, ASR Group owns and operates six sugar refineries, located in New York, California, Maryland, Louisiana, Canada and Mexico. In Europe, the company owns and operates sugar refineries in the United Kingdom, Portugal, and, with a joint venture partner, Italy. ASR Group also farms sugarcane and owns sugar mills in Mexico and Belize. The company's portfolio includes the leading brands Domino®, C&H®, Florida Crystals®, Redpath®, Tate & Lyle®, Lyle's®, Sidul® and Tellus®. ASR Group is owned by Florida-based cane sugar producers Florida Crystals Corporation and Sugar Cane Growers Cooperative of Florida. ASR Group and its parent companies jointly own Tellus Products, LLC, a maker of single-use, compostable tableware and foodservice products from sugarcane and other plant fibers. For more information, visit . About Bonumose, Inc. Bonumose, Inc. ( ) is an early-stage food ingredient and enzyme innovation company based in Albemarle County, Virginia. Bonumose is supported by global strategic investors and "food for health"-focused institutional investors, and an expanding network of global collaboration partners across the value chain. Bonumose developed and patented the methods for continuous production of high-purity rare sugars – such as Tagatose and Allulose – from low-cost, plant-based starch. Bonumose's cost-advantaged processes make possible the global mass-market adoption of healthy, great-tasting, fully-functional rare sugars. Bonumose also can upcycle by-product/sidestream starch left over from its supply chain partners' food production. Beyond food ingredients, Bonumose also is developing enzyme solutions for dietary supplements, crop protection, animal nutrition, and other globally-significant industries. Bonumose operates with a philosophy of Business as a Moral Imperative. About SGS Nutrasource Pharmaceutical and Nutraceutical Services Inc. SGS Nutrasource is a leading nutraceutical and pharmaceutical life sciences company focused on helping clients commercialize health and wellness products. In addition to a unique offering of clinical trial management, strategic and regulatory support services along with a state-of-the-art clinical trial site, SGS Nutrasource offers a series of third-party natural ingredient product certification programs (NutraStrong™, IFOS™, IKOS™, IGEN™, and IPRO™. SOURCE ASR Group

10 Aug 2023

·www.prnewswire.com

China Gaotang: Extending the Industrial Chain and Accelerating the Cultivation of Clusters

LIAOCHENG, China, Aug. 10, 2023 /PRNewswire/ -- This is a report from the Shandong office of Hong Kong Business Daily. Gaotang County, Shandong Province has solidly promoted new breakthroughs in major industrial projects and made every effort to push project construction work to a new level. This year, Shandong Aobo Biotechnology Co., Ltd., with a total investment of 150 million yuan, has entered the formal production stage of the biological enzyme production of aloketose project in Gaotang County. The project can achieve an annual sales revenue of 800 million yuan and profits and taxes of over 60 million yuan, injecting new momentum into the transformation of the enterprise into the biopharmaceutical health sector. The aloketose produced by the enterprise is a new type of functional monosaccharide with special health functions, with a sweetness equivalent to 70% of sucrose, zero sugar, zero fat, and zero calories. It has a promoting and protective effect on pancreatic islet cells, has similar taste and volume characteristics to sucrose, and can also react with amino acids or proteins in food in a Maillard manner. It is the ideal substitute for sucrose, with broad market prospects. Introduction by Wang Shuhua, Director of the R&D Center of Octopus Group. Adhere to high standard planning and continuously expand industrial clusters. Since the beginning of this year, Gaotang has implemented 57 key projects with a total investment of 24.834 billion yuan. Focusing on leading industrial chains such as equipment manufacturing, health food, paper and printing, we will make up for the shortcomings of the industrial chain, stretch the industrial chain, accelerate the cultivation of "wild goose formation" clusters and characteristic industrial clusters, and strive to form a group of industrial clusters with long product chains and strong industrial clustering. "Dynamically follow up on the construction status of existing key projects, promptly analyze and judge the existing difficulties and blockages in the same location, play the role of linkage service mechanism, organize relevant units to discuss, and strive to solve them in the shortest possible time. "Guo Chao, a member of the Party Group and Deputy Director of the Gaotang County Development and Reform Bureau, said. As of the end of June, 10 provincial-level key projects in Gaotang County have completed a cumulative investment of 1.425 billion yuan, and 17 municipal level key projects have completed a cumulative investment of 1.622 billion yuan. SOURCE Shandong Office of Hong Kong Business Daily

100 Deals associated with Sucrose

External Link

KEGG	Wiki	ATC	Drug Bank
D00025	Sucrose	-	DB02772

R&D Status

10 top R&D records.

to view more data

Indication	Highest Phase	Country/Location	Organization	Date
Bacterial Vaginosis	NDA/BLA	CN	Shenzhen Funuo Bio-Technology Co., Ltd.	29 Sep 2009
Bacterial Vaginosis	NDA/BLA	CN	Biomedical Engineering Centre Of Hebei Medical University	29 Sep 2009

Clinical Result

Indication

Phase

Evaluation

View All Results

Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


ASN2021	Not Applicable	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	36	Non-sucrose containing IVIG	qgmdsrdzkh(uexattpmwt) = hhahinsdjb zvxdipibsa (fonrywokjo, 88 - 159)	Positive	27 Oct 2021
				Sucrose containing IVIG	qgmdsrdzkh(uexattpmwt) = ybavhripac zvxdipibsa (fonrywokjo, 86 - 173)
NCT01438008 (CTgov)	Phase 4	Pain	9	24% sucrose po solution (Sucrose 24% po)	sarvjodtrg(iqtjrwijlq) = ygdeqbkhax popydaidiq (chtqeubwfg, habgjqfkyf - jgjdncsvmq) View more	-	19 Oct 2020
				Placebo po (Placebo po)	sarvjodtrg(iqtjrwijlq) = hcvhkfiail popydaidiq (chtqeubwfg, saaflxefyx - qwkfmhlmxk) View more
P0647 (ERA2020)	Not Applicable	Acute Kidney Injury Cyclosporine levels \| serum creatinine \| urinalysis ... View more	-	Sucrose-containing IVIG	bzujbemqga(vdqimfmnfv) = The patient subsequently developed acute kidney injury. The outcome was favorable with recovery of filtration rate to the baseline within 21 days without the need for dialysis. iiwrfiazeb (icffhqygjq ) View more	Negative	06 Jun 2020
NCT01785524 (CTgov)	Phase 2	Peripheral Arterial Disease \| Diabetes Mellitus, Type 2	18	Exercise Training (BR Juice (Beet-It Stamina Shot) & Supervised Exercise Training)	rylaovgjum(shjeqfbhin) = rszjbfapod ngkudlyvsa (pxvdomfkqg, jaiihhqpkd - syniefwgah) View more	-	05 Jan 2016
				Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training (BR Juice Placebo and Exercise Training)	rylaovgjum(shjeqfbhin) = kdpftxfeqq ngkudlyvsa (pxvdomfkqg, kgfbfoivgc - vyswtubrwt) View more
NCT01684930 (CTgov)	Phase 2	Peripheral Arterial Disease	32	Beetroot Juice (Beet-It Stamina Shot) & Supervised Exercise Training (BR Juice (Beet-It Stamina Shot) and Exercise Training)	yebawoymxy(drlmcfyejl) = kzagakrbvf qiwlyagnvy (zbqejwxuxw, erotxokglv - ulyzxxuiqf) View more	-	01 Jan 2016
				Placebo Comparator Beverage (Beet-It Stamina Shot) & Exercise Training (BR Juice Placebo and Exercise Training)	yebawoymxy(drlmcfyejl) = zvxymfxity qiwlyagnvy (zbqejwxuxw, xnqdssngek - tlanotdmbs) View more
NCT00694174 (Pubmed \| Clin J Pain)	Phase 4	Pain	56	Oral 24% sucrose	yngiszprpw(kxsvwjonyy) = odpdijtvns pgtwyblgif (qidpusaqyq )	-	01 May 2015
				Sterile water	yngiszprpw(kxsvwjonyy) = posjyquppy pgtwyblgif (qidpusaqyq )
ARVO2005	Not Applicable	Corneal Endothelial Cell Loss	-	Sucrose	ysgqptjtqt(hvstnktywt) = okbacvqfyn fiiprrtgbk (hwcoxyotdp, 288)	-	01 May 2005

Translational Medicine

Boost your research with our translational medicine data.

view full example data

Deal

Boost your decision using our deal data.

view full example data

Core Patent

Boost your research with our Core Patent data.

view full example data

Clinical Trial

Identify the latest clinical trials across global registries.

view full example data

Approval

Accelerate your research with the latest regulatory approval information.

view full example data

Regulation

Understand key drug designations in just a few clicks with Synapse.

view full example data

Get started for free today!

Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.

Start your data trial now!

Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.

Bio

Bio Sequences Search & Analysis

Chemical

Chemical Structures Search & Analysis