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Last update 19 Mar 2026
PF-08046031
Last update 19 Mar 2026
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms PF-08046031 |
Target |
Action inhibitors |
Mechanism CD228 inhibitors(Melanotransferrin inhibitors), Tubulin inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Molecular FormulaC11H22N4O4 |
InChIKeyAGGWFDNPHKLBBV-YUMQZZPRSA-N |
CAS Registry159858-33-0 |
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Related
1
Clinical Trials associated with PF-08046031NCT06799533
AN OPEN-LABEL PHASE 1 STUDY TO INVESTIGATE PF-08046031 IN ADULTS WITH ADVANCED MELANOMA AND OTHER SOLID TUMORS
100 Clinical Results associated with PF-08046031
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100 Translational Medicine associated with PF-08046031
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100 Patents (Medical) associated with PF-08046031
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100 Deals associated with PF-08046031
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Esophageal Carcinoma | Phase 1 | United States | 23 Jun 2025 | |
| Esophageal Carcinoma | Phase 1 | France | 23 Jun 2025 | |
| Esophageal Carcinoma | Phase 1 | Germany | 23 Jun 2025 | |
| Esophageal Carcinoma | Phase 1 | Netherlands | 23 Jun 2025 | |
| Esophageal Carcinoma | Phase 1 | Spain | 23 Jun 2025 | |
| Esophageal Carcinoma | Phase 1 | Sweden | 23 Jun 2025 | |
| Esophageal Carcinoma | Phase 1 | United Kingdom | 23 Jun 2025 | |
| Melanoma | Phase 1 | United States | 23 Jun 2025 | |
| Melanoma | Phase 1 | France | 23 Jun 2025 | |
| Melanoma | Phase 1 | Germany | 23 Jun 2025 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Translational Medicine
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Deal
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Core Patent
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Clinical Trial
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Approval
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Biosimilar
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Regulation
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