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Last update 28 Apr 2025
BB-1712
Last update 28 Apr 2025
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms BB 1712, BB1712 |
Target |
Action inhibitors |
Mechanism CD276 inhibitors(CD276 antigen inhibitors), TOP1 inhibitors(DNA topoisomerase I inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Structure/Sequence
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Related
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Clinical Trials associated with BB-1712CTR20250046
评价BB-1712在局部晚期/转移性实体瘤受试者中的安全性、耐受性、药代动力学和初步抗肿瘤活性的开放、多中心、剂量递增和剂量扩展的Ⅰ期研究
[Translation] An open-label, multicenter, dose-escalation and dose-expansion Phase I study to evaluate the safety, tolerability, pharmacokinetics, and preliminary antitumor activity of BB-1712 in subjects with locally advanced/metastatic solid tumors
100 Clinical Results associated with BB-1712
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100 Translational Medicine associated with BB-1712
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100 Patents (Medical) associated with BB-1712
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100 Deals associated with BB-1712
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Solid tumor | Phase 1 | China | 09 Apr 2025 | |
| Locally Advanced Malignant Solid Neoplasm | IND Approval | China | 15 Nov 2024 | |
| Metastatic Solid Tumor | IND Approval | China | 15 Nov 2024 | |
| Breast Cancer | Preclinical | China | 29 Apr 2025 | |
| Non-Small Cell Lung Cancer | Preclinical | China | 29 Apr 2025 | |
| Small Cell Lung Cancer | Preclinical | China | 29 Apr 2025 | |
| Stomach Cancer | Preclinical | China | 29 Apr 2025 |
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Regulation
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