Last update 24 May 2025

Pemafibrate/Tofogliflozin Hydrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
K-001
Target
PPARα x SGLT2
Action
agonists, inhibitors
Mechanism
PPARα agonists(Peroxisome proliferator-activated receptor α agonists), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization
Kowa Research Institute, Inc.
Active Organization
Kowa Co., Ltd.Kowa Co., Ltd.
Inactive Organization
Kowa Research Institute, Inc.
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC28H30N2O6
InChIKeyZHKNLJLMDFQVHJ-RUZDIDTESA-N
CAS Registry848259-27-8
View All Structures (2)

Related

1
Clinical Trials associated with Pemafibrate/Tofogliflozin Hydrate
NCT05722262
/ CompletedPhase 1
A Randomized, Open-Label, Six-Sequence, Three-Period Crossover Study to Demonstrate the Bioequivalence of Single Oral Administration of K-001 Relative to Single Oral Coadministration of Separate Tablets of K-877-ER Plus CSG452 in Healthy Adult Volunteers, and to Characterize the Food Effect on the Pharmacokinetics of K-001
100 Clinical Results associated with Pemafibrate/Tofogliflozin Hydrate
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100 Translational Medicine associated with Pemafibrate/Tofogliflozin Hydrate
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100 Patents (Medical) associated with Pemafibrate/Tofogliflozin Hydrate
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100 Deals associated with Pemafibrate/Tofogliflozin Hydrate
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R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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