Last update 17 Apr 2025

Clesacostat/Ervogastat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ervogastat/Clesacostat, PF 7055341, PF-05221304/PF-06865571
+ [2]
Target
ACC x DGAT2
Action
inhibitors
Mechanism
ACC inhibitors(Acetyl-CoA carboxylase inhibitors), DGAT2 inhibitors(Diacylglycerol O-acyltransferase 2 inhibitors)
Therapeutic Areas
Digestive System Disorders
Active Indication
Nonalcoholic Steatohepatitis
Inactive Indication-
Originator Organization
Pfizer Inc.Pfizer Inc.
Active Organization
Pfizer Japan, Inc.Pfizer Japan, Inc.
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (United States)
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Structure/Sequence

Molecular FormulaC28H30N4O5
InChIKeyLXZMHBHEXAELHH-UHFFFAOYSA-N
CAS Registry1370448-25-1
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Related

100 Clinical Results associated with Clesacostat/Ervogastat
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100 Translational Medicine associated with Clesacostat/Ervogastat
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100 Patents (Medical) associated with Clesacostat/Ervogastat
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100 Deals associated with Clesacostat/Ervogastat
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Nonalcoholic SteatohepatitisPhase 2
Japan
Pfizer Japan, Inc.Pfizer Japan, Inc.
28 Jul 2020
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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