Last update 26 Jul 2025

PT-819

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE)
Synonyms
PT 819, PT819
Target
CD3 x DLL3
Action
stimulants, inhibitors
Mechanism
CD3 stimulants(T cell surface glycoprotein CD3 stimulants), DLL3 inhibitors(Delta-like protein 3 inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects)
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication-
Inactive Indication
Small Cell Lung Cancer
Originator Organization
Phanes Therapeutics, Inc.Phanes Therapeutics, Inc.
Active Organization-
Inactive Organization
Phanes Therapeutics, Inc.Phanes Therapeutics, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with PT-819
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100 Translational Medicine associated with PT-819
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100 Patents (Medical) associated with PT-819
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100 Deals associated with PT-819
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Small Cell Lung CancerPreclinical
United States
Phanes Therapeutics, Inc.Phanes Therapeutics, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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