Last update 24 Jul 2025

PhOx-430

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PHOX-430
Target
GnT-V
Action
inhibitors
Mechanism
GnT-V inhibitors(alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase inhibitors)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
Advanced Malignant Solid NeoplasmBone metastasesGlioblastoma Multiforme+ [1]
Inactive Indication-
Originator Organization
Phost’in SAS
Active Organization
Phost’in SAS
Inactive Organization-
License Organization
Taiho Pharmaceutical Co., Ltd.Taiho Pharmaceutical Co., Ltd.Phost’in SAS
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with PhOx-430
NCT05495295
/ RecruitingPhase 1
An Adaptive First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Patients With Advanced Solid Tumours (PhAST Trial)
100 Clinical Results associated with PhOx-430
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100 Translational Medicine associated with PhOx-430
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100 Patents (Medical) associated with PhOx-430
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100 Deals associated with PhOx-430
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
France
Phost’in SAS
18 Jul 2022
Advanced Malignant Solid NeoplasmPhase 1
Italy
Phost’in SAS
18 Jul 2022
Bone metastasesPhase 1
France
Phost’in SAS
18 Jul 2022
Bone metastasesPhase 1
Italy
Phost’in SAS
18 Jul 2022
Glioblastoma MultiformePhase 1
France
Phost’in SAS
18 Jul 2022
Glioblastoma MultiformePhase 1
Italy
Phost’in SAS
18 Jul 2022
Liver metastasesPhase 1
France
Phost’in SAS
18 Jul 2022
Liver metastasesPhase 1
Italy
Phost’in SAS
18 Jul 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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