Last update 08 May 2025

NBTI-79

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
5-Amino-1,3-dioxane-linked Novel Bacterial Topoisomerase Inhibitor (NBTI) 79
Target
Bacterial DNA gyrase x Bacterial top IV
Action
inhibitors
Mechanism
Bacterial DNA gyrase inhibitors(Bacterial DNA gyrase inhibitors), Bacterial top IV inhibitors(Bacterial topoisomerase IV inhibitors)
Therapeutic Areas
Infectious Diseases
Active Indication
MRSA - Methicillin resistant Staphylococcus aureus infection
Inactive Indication-
Originator Organization
The Ohio State UniversityThe Ohio State UniversityEurofins Panlabs, Inc.
Active Organization
Eurofins Panlabs, Inc.The Ohio State UniversityThe Ohio State University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with NBTI-79
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100 Translational Medicine associated with NBTI-79
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100 Patents (Medical) associated with NBTI-79
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1
Literatures (Medical) associated with NBTI-79
28 Oct 2021Journal of Medicinal ChemistryQ1 · MEDICINE
Optimization of TopoIV Potency, ADMET Properties, and hERG Inhibition of 5-Amino-1,3-dioxane-Linked Novel Bacterial Topoisomerase Inhibitors: Identification of a Lead with In Vivo Efficacy against MRSA
Q1 · MEDICINE
100 Deals associated with NBTI-79
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
MRSA - Methicillin resistant Staphylococcus aureus infectionPreclinical
United States
Eurofins Panlabs, Inc.
06 Oct 2021
MRSA - Methicillin resistant Staphylococcus aureus infectionPreclinical
United States
The Ohio State UniversityThe Ohio State University
06 Oct 2021
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Clinical Result

Indication
Phase
Evaluation
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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