Last update 21 Nov 2024

Trophoblast antigen 2 tumour activated T-cell engager therapy (Janux Therapeutics)

Overview

Basic Info

Drug Type
Bispecific T-cell Engager (BiTE), Probody
Synonyms
TROP2TRACTr, Trophoblast Antigen 2 Tumour Activated TCell Engager therapy
Target
CD3 x Trop-2
Mechanism
CD3 modulators(T cell surface glycoprotein CD3 modulators), Trop-2 inhibitors(Tumor-associated calcium signal transducer 2 inhibitors)
Therapeutic Areas
NeoplasmsRespiratory DiseasesSkin and Musculoskeletal Diseases
Active Indication
Non-Small Cell Lung CancerTransitional Cell CarcinomaTriple Negative Breast Cancer
Inactive Indication-
Originator Organization
Janux Therapeutics, Inc.Janux Therapeutics, Inc.
Active Organization
Janux Therapeutics, Inc.Janux Therapeutics, Inc.
Inactive Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with Trophoblast antigen 2 tumour activated T-cell engager therapy (Janux Therapeutics)
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100 Translational Medicine associated with Trophoblast antigen 2 tumour activated T-cell engager therapy (Janux Therapeutics)
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100 Patents (Medical) associated with Trophoblast antigen 2 tumour activated T-cell engager therapy (Janux Therapeutics)
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100 Deals associated with Trophoblast antigen 2 tumour activated T-cell engager therapy (Janux Therapeutics)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPreclinical
US
Janux Therapeutics, Inc.Janux Therapeutics, Inc.
01 Nov 2022
Transitional Cell CarcinomaPreclinical
US
Janux Therapeutics, Inc.Janux Therapeutics, Inc.
01 Nov 2022
Triple Negative Breast CancerPreclinical
US
Janux Therapeutics, Inc.Janux Therapeutics, Inc.
01 Nov 2022
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Clinical Result

Indication
Phase
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Approval

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Regulation

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