Delving into the Latest Updates on TimoD with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms-

Target

β-adrenoceptors

Action

antagonists

Mechanism

β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)

Therapeutic Areas

Eye Diseases

Active Indication

Glaucoma

Inactive Indication-

Originator Organization

EyeD Pharma SA

Active Organization

EyeD Pharma SA

Inactive Organization-

License Organization-

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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A 74-yr-old man presented with 3-wk appearance of eczematous pruritic lesions on both eyelids and the periorbital region, after 4 mo of treatment for glaucoma with three differ- ent eyedrops.After informed consent, patch test was performed with the Societa Italiana di Dermatologia Allergologica Professionale eAmbientale (SIDAPA) baseline series (FIRMA, Florence, Italy), and the patient′s own eyedrops as is: Combigan (Allergan Inc, Wesport Co Mayo, Ireland) (BT 2 mg/mL, timolol maleate 6.8 mg/mL, benzalkonium chloride 0.05 mg/mL, monobasic sodium phosphate monohydrate, dibasic sodium phosphate eptahydrate, hydrochloric acid, and sodium hydroxide); Xalatan (Pfizer, Madrid, Spain) (latanoprost 0.05 mg/mL, benazalkonium chloride 0.02 mg/mL, sodium chloride, monobasic sodium phosphate monohydrate, anhydrous dibasic sodium phosphate); and Timod (Visufarma, Rome, Italy) (timolol 3.42 mg/mL, monobasic sodium phosphate, and dibasic sodium phosphate).Readings were performed on day (D) 2 and D3. A pos. reaction (+) to Combigan was recorded on both D2 and D3.A diagnosis of ACD probably caused by BT contained in eyedrops was made.Hence, the patient was prescribed Travoprost EG eyedrops (STADA) (travoprost, benzalkonium chloride, macrogol glyc- erol hydroxy stearate 40, trometamol, disodium edetate, boric acid, mannitol, sodium hydroxide, purified water), with complete resolution of the skin lesions and good control of glaucoma.

100 Deals associated with TimoD

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