Last update 21 Nov 2024

PSD-506

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
M2 receptor x M3 receptor
Mechanism
M2 receptor antagonists(Muscarinic acetylcholine receptor M2 antagonists), M3 receptor agonists(Muscarinic acetylcholine receptor M3 agonists)
Therapeutic Areas
Nervous System DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
Prostatic HyperplasiaUrinary Bladder, NeurogenicUrinary Bladder, Overactive+ [1]
Originator Organization
F. Hoffmann-La Roche Ltd.
Active Organization-
Inactive Organization
Plethora Solutions Ltd.F. Hoffmann-La Roche Ltd.
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC22H37N3O3S
InChIKeyLKSVNYOHPRHYSG-IBGZPJMESA-N
CAS Registry754177-77-0

Related

6
Clinical Trials associated with PSD-506
EUCTR2006-002663-11-GB / Not yet recruitingPhase 2
An open-label, escalating dose, proof of concept study to determine the effects of single oral doses of PSD506 on unstable urinary bladder contractions induced by volume provocation in subjects with detrusor hyper-reflexia secondary to spinal injuries above T12
ISRCTN81647490 / CompletedPhase 1
An open-label, escalating dose, proof of concept study to determine the effects of single oral doses of PSD506 on unstable urinary bladder contractions induced by volume provocation in subjects with detrusor hyper-reflexia secondary to spinal injuries above T12
EUCTR2006-002055-32-GB / Not yet recruitingNot Applicable
A double-blind, placebo controlled, pilot study to assess the safety and preliminary efficacy of PSD506 in treatment-naïve or previously treated (washed out) patients with benign prostatic obstruction (BPO) and lower urinary tract symptoms (LUTS) - PSD506-OAB-004
100 Clinical Results associated with PSD-506
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100 Translational Medicine associated with PSD-506
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100 Patents (Medical) associated with PSD-506
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100 Deals associated with PSD-506
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Prostatic HyperplasiaPhase 2-
Plethora Solutions Ltd.
-
Prostatic HyperplasiaPhase 2-
F. Hoffmann-La Roche Ltd.
-
Urinary Bladder, NeurogenicPhase 2
GB
Plethora Solutions Ltd.
-
Urinary Bladder, OveractivePhase 2
GB
Plethora Solutions Ltd.
-
Urinary Bladder, OveractivePhase 2-
F. Hoffmann-La Roche Ltd.
-
Urinary IncontinencePhase 2-
Plethora Solutions Ltd.
-
Urinary IncontinencePhase 2-
F. Hoffmann-La Roche Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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