Last update 07 Jun 2025

YX-2-233

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
YX-2-233
Target
CDK4 x CDK6
Action
inhibitors
Mechanism
CDK4 inhibitors(Cyclin-dependent kinase 4 inhibitors), CDK6 inhibitors(Cyclin-dependent kinase 6 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases
Active Indication-
Inactive Indication
Philadelphia positive acute lymphocytic leukaemia
Originator Organization
Thomas Jefferson UniversityThomas Jefferson University
Active Organization-
Inactive Organization
Thomas Jefferson UniversityThomas Jefferson University
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC65H79Cl2N13O6
InChIKeyIGNFCLYXCYPVEB-NXURCQBISA-N
CAS Registry-

Related

100 Clinical Results associated with YX-2-233
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100 Translational Medicine associated with YX-2-233
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100 Patents (Medical) associated with YX-2-233
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100 Deals associated with YX-2-233
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Philadelphia positive acute lymphocytic leukaemiaPreclinical
United States
Thomas Jefferson UniversityThomas Jefferson University
30 Apr 2020
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Clinical Result

Indication
Phase
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Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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