[Translation] A randomized, double-blind, placebo-controlled Phase Ib/IIa clinical trial to evaluate the efficacy and safety of TQA3605 alone or in combination with nucleoside (acid) analogs in patients with treatment-naive and treatment-experienced chronic hepatitis B
主要目的:
评价TQA3605单药或联合核苷(酸)类似物(NAs)在初治及经治慢性乙型肝炎患者中的安全性;
次要目的:
1.评价TQA3605单药或联合核苷(酸)类似物在初治及经治慢性乙型肝炎患者中的有效性;
评价TQA3605在初治慢性乙型肝炎患者中多剂量、多次给药后的药代动力学特征。
[Translation] Main purpose:
To evaluate the safety of TQA3605 alone or in combination with nucleoside (acid) analogs (NAs) in patients with chronic hepatitis B who have undergone treatment for the first time or who have undergone treatment for the first time;
Secondary purpose:
1. To evaluate the efficacy of TQA3605 alone or in combination with nucleoside (acid) analogs in patients with chronic hepatitis B who have undergone treatment for the first time or who have undergone treatment for the first time;
To evaluate the pharmacokinetic characteristics of TQA3605 after multiple doses and multiple administrations in patients with chronic hepatitis B who have undergone treatment for the first time.