Last update 08 May 2025

AZD-9793

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms
Target
CD8 x GPC3 x TCR
Action
modulators, inhibitors
Mechanism
CD8 modulators(Cluster of differentiation 8 modulators), GPC3 inhibitors(Glypican-3 inhibitors), TCR modulators(T-cell receptor modulators)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Hepatocellular CarcinomaSolid tumor
Inactive Indication-
Originator Organization
AstraZeneca PLCAstraZeneca PLC
Active Organization
AstraZeneca PLCAstraZeneca PLCAstraZeneca, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with AZD-9793
NCT06795022
/ RecruitingPhase 1/2
A Modular Phase I/II Open-label Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD9793, a T Cell-engaging Antibody Targeting Glypican-3 (GPC3) in Adult Participants With Advanced or Metastatic Solid Tumours (RHEA-1)
100 Clinical Results associated with AZD-9793
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100 Translational Medicine associated with AZD-9793
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100 Patents (Medical) associated with AZD-9793
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100 Deals associated with AZD-9793
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatocellular CarcinomaPhase 2
United States
AstraZeneca PLCAstraZeneca PLC
27 Mar 2025
Hepatocellular CarcinomaPhase 2
Hong Kong
AstraZeneca PLCAstraZeneca PLC
27 Mar 2025
Hepatocellular CarcinomaPhase 2
Japan
AstraZeneca PLCAstraZeneca PLC
27 Mar 2025
Solid tumorPreclinical
United States
AstraZeneca, Inc.
05 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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