CS-060380

Primary purpose: To investigate the safety and tolerability of single and multiple oral administration of CS060380 in healthy and LDL-C elevated subjects Secondary purpose: To investigate the PK characteristics of single and multiple oral administration of CS060380 in healthy and LDL-C elevated subjects, and to evaluate the effect of food on the PK characteristics of CS060380 after a single dose in healthy subjects Exploratory purpose: To explore the PD characteristics, effect on thyroid function, and effect on QT interval of multiple oral administration of CS060380 in LDL-C elevated subjects