Last update 06 Nov 2025

CS-060380

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CS 060380, CS060380
Target
THR-β
Action
agonists
Mechanism
THR-β agonists(Thyroid hormone receptor beta agonists)
Therapeutic Areas
Digestive System DisordersEndocrinology and Metabolic DiseaseOther Diseases
Active Indication
Metabolic Dysfunction Associated SteatohepatitisHyper LDL cholesterolaemiaHomozygous familial hypercholesterolemia
Inactive Indication-
Originator Organization
Cascade Pharmaceuticals, Inc.Cascade Pharmaceuticals, Inc.
Active Organization
Cascade Pharmaceuticals, Inc.Cascade Pharmaceuticals, Inc.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with CS-060380
NCT07198386
/ RecruitingPhase 2
A Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of CS060380 Tablets in Patients With Non-alcoholic Steatohepatitis (NASH).
NCT06573528
/ CompletedPhase 1
A Phase I Study Evaluating the Safety, Tolerability, Pharmacokinetics and Food Effect of Randomized, Double-Blind, Placebo-Controlled Single and Multiple Dose Escalations of CS060380 in Healthy and Elevated LDL-C Subjects
100 Clinical Results associated with CS-060380
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100 Translational Medicine associated with CS-060380
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100 Patents (Medical) associated with CS-060380
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100 Deals associated with CS-060380
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metabolic Dysfunction Associated SteatohepatitisPhase 2
China
Cascade Pharmaceuticals, Inc.Cascade Pharmaceuticals, Inc.
29 Sep 2025
Hyper LDL cholesterolaemiaPhase 1
China
Cascade Pharmaceuticals, Inc.Cascade Pharmaceuticals, Inc.
03 Sep 2024
Homozygous familial hypercholesterolemiaIND Approval
China
Cascade Pharmaceuticals, Inc.Cascade Pharmaceuticals, Inc.
26 Nov 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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