[Translation] Safety, tolerability and pharmacokinetics of single and multiple subcutaneous injections of SHR-6934 injection in healthy subjects: a randomized, double-blind, dose-escalation, placebo-controlled phase I clinical trial
主要目的:
评估单次和多次皮下注射SHR-6934注射液在健康受试者中的安全性和耐受性。
次要目的: 评估单次和多次皮下注射SHR-6934注射液在健康受试者中的药代动力学(PK)特征和免疫原性;
评估SHR-6934对QT间期的影响。
[Translation] Primary objective:
To evaluate the safety and tolerability of single and multiple subcutaneous injections of SHR-6934 injection in healthy subjects.
Secondary objectives: To evaluate the pharmacokinetic (PK) characteristics and immunogenicity of single and multiple subcutaneous injections of SHR-6934 injection in healthy subjects;
To evaluate the effect of SHR-6934 on the QT interval.