Last update 03 Apr 2025

ABO-2203

Overview

Basic Info

Drug Type
mRNA encoding bispecific antibody, Bispecific T-cell Engager (BiTE)
Synonyms
ABO 2203, ABO2203
Target
CD19 x CD3
Action
modulators
Mechanism
CD19 modulators(B-lymphocyte antigen CD19 modulators), CD3 modulators(T cell surface glycoprotein CD3 modulators)
Therapeutic Areas
Immune System DiseasesNervous System DiseasesSkin and Musculoskeletal Diseases+ [2]
Active Indication
Autoimmune DiseasesIdiopathic Inflammatory MyopathiesLupus Nephritis+ [2]
Inactive Indication-
Originator Organization
Suzhou Abogen Biosciences Co., Ltd.Suzhou Abogen Biosciences Co., Ltd.
Active Organization
Suzhou Guangxin Biotechnology Co., Ltd.Suzhou Abogen Biosciences Co., Ltd.Suzhou Abogen Biosciences Co., Ltd.
Inactive Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with ABO-2203
NCT06747156
/ Not yet recruitingEarly Phase 1IIT
A Clinical Study to Investigate Safety, Tolerability, and Preliminary Efficacy of mRNA Encoding CD19/CD3 T Cell Engager (ABO2203) in Patients With Refractory Autoimmune Diseases
100 Clinical Results associated with ABO-2203
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100 Translational Medicine associated with ABO-2203
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100 Patents (Medical) associated with ABO-2203
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100 Deals associated with ABO-2203
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Autoimmune DiseasesPhase 1
China
Suzhou Abogen Biosciences Co., Ltd.Suzhou Abogen Biosciences Co., Ltd.
24 Dec 2024
Idiopathic Inflammatory MyopathiesPhase 1
China
Suzhou Guangxin Biotechnology Co., Ltd.
01 Dec 2024
Lupus NephritisPhase 1
China
Suzhou Guangxin Biotechnology Co., Ltd.
01 Dec 2024
Rheumatoid ArthritisPhase 1
China
Suzhou Guangxin Biotechnology Co., Ltd.
01 Dec 2024
Scleroderma, SystemicPhase 1
China
Suzhou Guangxin Biotechnology Co., Ltd.
01 Dec 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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