Last update 11 Oct 2025

PPL-003

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
PPL 003, PPL003
Target
NF-κB
Action
inhibitors
Mechanism
NF-κB inhibitors(Nuclear factor NF-kappa-B complex inhibitors)
Therapeutic Areas
Eye Diseases
Active Indication-
Inactive Indication
Dry Eye SyndromesUveitis
Originator Organization
AlphaTON Capital Corp.AlphaTON Capital Corp.
Active Organization-
Inactive Organization
AlphaTON Capital Corp.AlphaTON Capital Corp.EyGen Ltd.
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Related

100 Clinical Results associated with PPL-003
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100 Translational Medicine associated with PPL-003
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100 Patents (Medical) associated with PPL-003
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100 Deals associated with PPL-003
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Dry Eye SyndromesPreclinical
Canada
AlphaTON Capital Corp.AlphaTON Capital Corp.
12 Jul 2017
Dry Eye SyndromesPreclinical
Canada
EyGen Ltd.
12 Jul 2017
UveitisPreclinical
Canada
EyGen Ltd.
30 Nov 2016
UveitisPreclinical
Canada
AlphaTON Capital Corp.AlphaTON Capital Corp.
30 Nov 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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