Last update 09 Apr 2025

Metformin/Leucine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
L-leucine/metformin, Leucine/metformin, Metformin/L-leucine
+ [1]
Target
PRKAB1
Action
activators
Mechanism
PRKAB1 activators(Protein kinase AMP-activated non-catalytic subunit beta 1 activators)
Therapeutic Areas
Endocrinology and Metabolic Disease
Active Indication-
Inactive Indication
Diabetes Mellitus, Type 2
Originator Organization
Nusirt Sciences, Inc.Nusirt Sciences, Inc.
Active Organization-
Inactive Organization
Nusirt Sciences, Inc.Nusirt Sciences, Inc.
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC6H13NO2
InChIKeyROHFNLRQFUQHCH-YFKPBYRVSA-N
CAS Registry61-90-5
View All Structures (2)

Related

100 Clinical Results associated with Metformin/Leucine
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100 Translational Medicine associated with Metformin/Leucine
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100 Patents (Medical) associated with Metformin/Leucine
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11
Literatures (Medical) associated with Metformin/Leucine
01 Jan 1976Doklady Akademii nauk SSSR
[Subcellular localization of dipeptide hydrolysis in the small intestine of animals].
01 Jun 1975Indian journal of biochemistry & biophysics
Chemical modification of peptide antibiotics : Part III. Biological activities of some ethanolamine and tryptophan derivatives and of some polypeptides containing tryptophan.
01 Mar 1975Applied microbiology
Bacterial Metabolism of Arylsulfonates: Role of meta Cleavage in Benzene Sulfonate Oxidation by Pseudomonas testosteroni
100 Deals associated with Metformin/Leucine
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetes Mellitus, Type 2Phase 2
United States
Nusirt Sciences, Inc.Nusirt Sciences, Inc.
01 Aug 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Approval

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Regulation

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