Superficial fungal infections are among the most commonly managed skin problems by general practitioners. Although evidence shows combination antifungal/corticosteroid topicals are more expensive and less effective than single-agent antifungals, practitioners continue to prescribe combination agents. We examined current prescription trends of 2 combination antifungal/corticosteroid medications, Lotrisone and Mycolog-II.

01 Dec 1978·American Journal of Health-System Pharmacy

Successful Treatment of Acrodermatitis Enteropathica with Zinc Sulfate

Article

Author: Steiner, Gilbert A.

A case of a 22-month-old child with acrodermatitis enteropathica (AE) is reported. At five months of age, the patient experienced generalized oral and cutaneous candidiasis for which she was treated with nystatin and iodochlorhydroxyquin-hydrocortisone. She then had to be treated for secondary infection of the lesions. After three months, the cycle repeated, and the patient was treated with topical clotrimazole, Mycolog (nystatin, gramicidin, neomycin sulfate, triamcinolone acetonide) and oral nystatin. After a worsening of her condition, she was admitted to a hospital where she was treated initially with procaine penicillin G, then methicillin sodium and gentamicin sulfate. Treatment with zinc sulfate, 50 mg t.i.d., was initiated when laboratory studies showed a serum zinc level of 60 microgram/dl. Skin lesions were 99% resolved and serum zinc increased to 118 microgram/dl after 17 days of zinc sulfate therapy. Previous case reports and studies of the clinical features, treatment and pathogenesis of AE are reviewed.

01 Apr 1976·Archives of Dermatology

Sensitization and Induction

Article

Author: John W. Petrozzi ; Ronald N. Shore

A patient with a history of allergic reaction to an antibiotic cream (Mycolog [mixture of nystatin, neomycin sulfate, gramicidin, and triamcinolone acetonide]) was treated with aminophylline. A generalized exfoliative dermatitis resulted. The reaction was attributable to ethylenediamine hydrochloride, which is a component of both agents. Recognition of the potential for systemic medications to induce similar reactions in patients who are allergic to related topical preparations is important when prescribing systemic agents.

100 Deals associated with Nystatin/Triamcinolone acetonide

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KEGG	Wiki	ATC	Drug Bank
-	-	S02CA04 D07BB03 G01AA51 D07CB01	-

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