Last update 30 May 2025

Chlorthalidone/Metoprolol Tartrate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lopressidone
Target
NCC x β1-adrenergic receptor
Action
inhibitors, antagonists
Mechanism
NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
Hypertension
Originator Organization
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
Active Organization-
Inactive Organization
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
License Organization-
Drug Highest PhaseWithdrawn
First Approval Date
United States (31 Dec 1987),
Hypertension
Regulation-
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Structure/Sequence

Molecular FormulaC14H11ClN2O4S
InChIKeyJIVPVXMEBJLZRO-UHFFFAOYSA-N
CAS Registry77-36-1
View All Structures (2)

Related

100 Clinical Results associated with Chlorthalidone/Metoprolol Tartrate
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100 Translational Medicine associated with Chlorthalidone/Metoprolol Tartrate
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100 Patents (Medical) associated with Chlorthalidone/Metoprolol Tartrate
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100 Deals associated with Chlorthalidone/Metoprolol Tartrate
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
United States
Novartis Pharmaceuticals Corp.Novartis Pharmaceuticals Corp.
31 Dec 1987
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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